Sensitivity means the proportion of people with a disease that have a positive test, whereas specificity means the proportion of people without the disease that have a negative test. It has an overall sensitivity of 76.8% for all PCR positive individuals but detects over 95% of individuals with high viral loads, and minimal difference between the ability of the test to pick up viral antigens in symptomatic and asymptomatic individuals.The specificity of the test was recorded as 99.68% - the overall false positive rate was 0.32%, although this was lowered to 0.06% in a lab setting.The results of the Innova evaluation published today show: The evaluation published today concludes that the Innova, and other tests which meet PHE and Oxford’s standards, should be used in asymptomatic, as they offer the advantage of reducing risk and increasing capacity in addition to Lighthouse and NHS labs. The fast turnaround also allows positive people to isolate quickly also reducing spread. PHE Porton Down’s labs have shown four lateral flow tests to have a sensitivity of more than 70% of all PCR positive cases but importantly catch all those with high viral loads, meaning they are effective in identifying the cases who are infectious and are most likely to transmit the disease. Six made it to the third phase, and the Innova SARS-CoV-2 Antigen Rapid Qualitative Test, the test being used in the Liverpool pilot, is nearing completion of the four-stage process. This includes the test being used in Liverpool, and those that are being sent to Directors of Public Health across the country to use for their local communities, and are also being used in schools, universities and workplace settings.įorty different lateral flow devices were put forward, of which nine met the criteria to continue to full evaluation. PHE’s Porton Down lab and University of Oxford undertook this work and have since been putting a number of tests through a four-phase assessment process. The devices are designed to be intuitive and require minimal training to operate, and PHE and the University of Oxford are now looking at how this test could be self-administered. The swabbing and processing of these tests must currently be conducted at a dedicated testing site by a trained personnel. These new tests are being piloted across England, including a two-week whole-city pilot in Liverpool, which was launched last week. ![]() ![]() Lateral Flow Tests are rapid turnaround tests that can process COVID-19 samples on site without the need for laboratory equipment, with most generating results in under half an hour.
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